Title : Fenretinide via NOXA Induction, Enhanced Activity of the BCL-2 Inhibitor Venetoclax in High BCL-2-Expressing Neuroblastoma Preclinical Models.

Pub. Date : 2019 Dec

PMID : 31484706






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Fenretinide (4-HPR) is a cytotoxic retinoid with clinical activity in recurrent neuroblastoma and venetoclax (ABT-199) is a selective inhibitor of the antiapoptotic protein B-cell lymphoma-2 (BCL-2). Fenretinide haptoglobin-related protein Homo sapiens