Title : An Algal Metabolite-Based PPAR-γ Agonist Displayed Anti-Inflammatory Effect via Inhibition of the NF-κB Pathway.

Pub. Date : 2019 May 30

PMID : 31151271






4 Functional Relationships(s)
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1 In our previous study, a synthetic compound, (+)-(R,E)-6a1, that incorporated the key structures of anti-inflammatory algal metabolites and the endogenous peroxisome proliferator-activated receptor gamma (PPAR-gamma) ligand 15-deoxy- 12,14-prostaglandin J2 (15d-PGJ2), exerted significant PPAR-gamma transcriptional activity. 15-deoxy-delta(12,14)-prostaglandin J2 peroxisome proliferator activated receptor gamma Mus musculus
2 In our previous study, a synthetic compound, (+)-(R,E)-6a1, that incorporated the key structures of anti-inflammatory algal metabolites and the endogenous peroxisome proliferator-activated receptor gamma (PPAR-gamma) ligand 15-deoxy- 12,14-prostaglandin J2 (15d-PGJ2), exerted significant PPAR-gamma transcriptional activity. 15-deoxy-delta(12,14)-prostaglandin J2 peroxisome proliferator activated receptor gamma Mus musculus
3 In our previous study, a synthetic compound, (+)-(R,E)-6a1, that incorporated the key structures of anti-inflammatory algal metabolites and the endogenous peroxisome proliferator-activated receptor gamma (PPAR-gamma) ligand 15-deoxy- 12,14-prostaglandin J2 (15d-PGJ2), exerted significant PPAR-gamma transcriptional activity. 15-deoxy-delta(12,14)-prostaglandin J2 peroxisome proliferator activated receptor gamma Mus musculus
4 In our previous study, a synthetic compound, (+)-(R,E)-6a1, that incorporated the key structures of anti-inflammatory algal metabolites and the endogenous peroxisome proliferator-activated receptor gamma (PPAR-gamma) ligand 15-deoxy- 12,14-prostaglandin J2 (15d-PGJ2), exerted significant PPAR-gamma transcriptional activity. 15-deoxy-delta(12,14)-prostaglandin J2 peroxisome proliferator activated receptor gamma Mus musculus