Title : Synergistic antitumour effects of triptolide plus 10-hydroxycamptothecin onbladder cancer.

Pub. Date : 2019 Jul

PMID : 31063955






1 Functional Relationships(s)
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1 RESULTS: The flow cytometry and western blot results indicated that compared to TPL or HCPT treatment alone, combination treatment of HCPT and TPL significantly induced cell cycle arrest at the G1 phase via suppressing CDK4, CDK6 and CyclinD1 in the EJ and UMUC3 bladder cancer cell lines. hydroxycamptothecinum cyclin dependent kinase 4 Homo sapiens