Title : Bimetallic ZrHf-based metal-organic framework embedded with carbon dots: Ultra-sensitive platform for early diagnosis of HER2 and HER2-overexpressed living cancer cells.

Pub. Date : 2019 Jun 1

PMID : 30952013






4 Functional Relationships(s)
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1 As compared with the pristine ZrHf-MOF, the CDs@ZrHf-MOF-based electrochemical aptasensor displays better sensing performances toward both HER-2 and MCF-7 cells, giving an extremely low detection limit of 19 fg mL-1 (HER2 concentration range: 0.001-10 ng mL-1) and 23 cell mL-1 (cell concentration range: 1 x 102~1 x 105 cell mL-1), with good selectivity, stability, reproducibility, and acceptable applicability. cds L1 cell adhesion molecule Mus musculus
2 As compared with the pristine ZrHf-MOF, the CDs@ZrHf-MOF-based electrochemical aptasensor displays better sensing performances toward both HER-2 and MCF-7 cells, giving an extremely low detection limit of 19 fg mL-1 (HER2 concentration range: 0.001-10 ng mL-1) and 23 cell mL-1 (cell concentration range: 1 x 102~1 x 105 cell mL-1), with good selectivity, stability, reproducibility, and acceptable applicability. cds L1 cell adhesion molecule Mus musculus
3 As compared with the pristine ZrHf-MOF, the CDs@ZrHf-MOF-based electrochemical aptasensor displays better sensing performances toward both HER-2 and MCF-7 cells, giving an extremely low detection limit of 19 fg mL-1 (HER2 concentration range: 0.001-10 ng mL-1) and 23 cell mL-1 (cell concentration range: 1 x 102~1 x 105 cell mL-1), with good selectivity, stability, reproducibility, and acceptable applicability. cds L1 cell adhesion molecule Mus musculus
4 As compared with the pristine ZrHf-MOF, the CDs@ZrHf-MOF-based electrochemical aptasensor displays better sensing performances toward both HER-2 and MCF-7 cells, giving an extremely low detection limit of 19 fg mL-1 (HER2 concentration range: 0.001-10 ng mL-1) and 23 cell mL-1 (cell concentration range: 1 x 102~1 x 105 cell mL-1), with good selectivity, stability, reproducibility, and acceptable applicability. cds L1 cell adhesion molecule Mus musculus