Title : Boron delivery for boron neutron capture therapy targeting a cancer-upregulated oligopeptide transporter.

Pub. Date : 2019 Mar

PMID : 30833090






2 Functional Relationships(s)
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1 Here, by using dipeptides of BPA and tyrosine (BPA-Tyr and Tyr-BPA), we propose a novel strategy of selective boron delivery into tumor cells via oligopeptide transporter PEPT1 upregulated in various cancers. Dipeptides solute carrier family 15 member 1 Homo sapiens
2 The BPA-containing dipeptides would have a potential for the development of novel boron carriers targeting PEPT1. Dipeptides solute carrier family 15 member 1 Homo sapiens