Title : Subverted regulation of Nox1 NADPH oxidase-dependent oxidant generation by protein disulfide isomerase A1 in colon carcinoma cells with overactivated KRas.

Pub. Date : 2019 Feb 13

PMID : 30760703






2 Functional Relationships(s)
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Protein Name
Organism
1 Transfection of Rac1G12V active mutant into HKE3 cells induced PDIA1 to become restrictive of Nox1-dependent superoxide, while in HCT116 cells treated with Rac1 inhibitor, PDIA1 became supportive of superoxide. Superoxides Rac family small GTPase 1 Homo sapiens
2 Transfection of Rac1G12V active mutant into HKE3 cells induced PDIA1 to become restrictive of Nox1-dependent superoxide, while in HCT116 cells treated with Rac1 inhibitor, PDIA1 became supportive of superoxide. Superoxides Rac family small GTPase 1 Homo sapiens