Title : IDH2 inhibition enhances proteasome inhibitor responsiveness in hematological malignancies.

Pub. Date : 2019 Jan 10

PMID : 30455381






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Specifically, CFZ treatment reduced the expression of nicotinamide phosphoribosyltransferase (NAMPT), thus limiting IDH2 activation through the NAD+-dependent deacetylase SIRT3. NAD sirtuin 3 Homo sapiens