Title : Combining bioinformatics, cheminformatics, functional genomics and whole organism approaches for identifying epigenetic drug targets in Schistosoma mansoni.

Pub. Date : 2018 Dec

PMID : 30455056






1 Functional Relationships(s)
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1 The most active compounds (L10 - pirarubicin > L8 - danunorubicin hydrochloride) were subsequently tested against juvenile (3 wk old) and mature (7 wk old) schistosome stages and found to impede motility, suppress egg production and affect tegumental surfaces. l8 - danunorubicin hydrochloride immunoglobulin kappa variable 3-7 (non-functional) Homo sapiens