Title : Asymmetric synthesis and biological evaluation of imidazole- and oxazole-containing synthetic lipoxin A4 mimetics (sLXms).

Pub. Date : 2019 Jan 15

PMID : 30419493






2 Functional Relationships(s)
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1 The potential interaction of the imidazoles/oxazoles with the molecular target of LXs, i.e. G-protein coupled receptor (GPCR) Formyl Peptide Receptor 2 (ALX/FPR2) was investigated using a cell system where ALX/FPR2 is coupled to the Galphaq subunit and receptor interaction determined by mobilisation of intracellular calcium. Imidazoles hematopoietic SH2 domain containing Homo sapiens
2 The potential interaction of the imidazoles/oxazoles with the molecular target of LXs, i.e. G-protein coupled receptor (GPCR) Formyl Peptide Receptor 2 (ALX/FPR2) was investigated using a cell system where ALX/FPR2 is coupled to the Galphaq subunit and receptor interaction determined by mobilisation of intracellular calcium. Imidazoles hematopoietic SH2 domain containing Homo sapiens