Title : Roles of extrahepatic lipolysis and the disturbance of hepatic fatty acid metabolism in TNF-α -induced hepatic steatosis.

Pub. Date : 2019 Jan 1

PMID : 30359672






1 Functional Relationships(s)
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1 TNF-alpha led to the activation of extrahepatic lipolysis demonstrated by the increase of serum free fatty acid (FFA) level, and the increased protein levels of adipose triglyceride lipase (ATGL) and phosphorylated hormone-sensitive lipase (HSL) in mice epididymal adipose tissues, but had no significant effects on the protein levels of sterol regulatory element binding protein 1c (SREBP-1c) and peroxisomal proliferator activation receptor alpha (PPAR-alpha) in mice liver. Fatty Acids, Nonesterified tumor necrosis factor Mus musculus