Title : Sub-toxic exposure to lindane activates redox sensitive kinases and impairs insulin signaling in muscle cell culture: The possible mechanism of lindane-induced insulin resistance.

Pub. Date : 2019 Feb

PMID : 30248393






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 HSP70 was induced and insulin signaling as measured from tyrosine phosphorylation of insulin receptor (IR) & insulin receptor substrate-1 (IRS-1) and serine phosphorylation of Akt was attenuated in comparison to those in untreated myotubes. Tyrosine insulin receptor substrate 1 Rattus norvegicus
2 HSP70 was induced and insulin signaling as measured from tyrosine phosphorylation of insulin receptor (IR) & insulin receptor substrate-1 (IRS-1) and serine phosphorylation of Akt was attenuated in comparison to those in untreated myotubes. Tyrosine insulin receptor substrate 1 Rattus norvegicus