Title : Interaction of IL 1 and TPA in modulation of eosinophil function.

Pub. Date : 1986 Dec 1

PMID : 3023484






3 Functional Relationships(s)
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1 Superoxide anion production by eosinophils stimulated with standard doses of the stimulant phorbol myristic acetate (TPA) (1 microgram/ml) was augmented approximately 20% by preincubation with IL 1. Superoxides interleukin 1 beta Homo sapiens
2 At suboptimal doses of TPA, there was a dose-dependent inhibition of superoxide anion production in the presence of IL 1. Superoxides interleukin 1 beta Homo sapiens
3 When IL 1 was added to eosinophils stimulated by TPA in the presence of calcium ionophore, there was a dose-dependent increase in superoxide anion production. Superoxides interleukin 1 beta Homo sapiens