Title : The role of cAMP and prostaglandins in gastric acid secretion after pentagastrin administration.

Pub. Date : 1986 Jul

PMID : 3019744






2 Functional Relationships(s)
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1 The role of cAMP and prostaglandins as specific intracellular effectors of gastrin action at the level of the parietal cells has not been sufficiently clarified. Cyclic AMP gastrin Homo sapiens
2 Our results suggest that: 1. an increase in intracellular cAMP may be the basis of the stimulatory effect of gastrin on gastric acid secretion 2. a decrease in the synthesis of prostaglandins may lead to a greater gastric acid response after pentagastrin. Cyclic AMP gastrin Homo sapiens