Title : β-Heregulin impairs EGF induced PLC-γ1 signalling in human breast cancer cells.

Pub. Date : 2018 Dec

PMID : 30165102






1 Functional Relationships(s)
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1 Western blot studies showed that both ErbB receptor and PLC-gamma1 tyrosine phosphorylation levels were diminished in EGF and beta-Heregulin co-treated MDA-NEO and MDA-HER2 cells, which was further correlated to a significantly impaired calcium influx. Tyrosine epidermal growth factor Homo sapiens