Title : Fingolimod (FTY720) is not protective in the subacute MPTP mouse model of Parkinson's disease and does not lead to a sustainable increase of brain-derived neurotrophic factor.

Pub. Date : 2018 Dec

PMID : 30152864






2 Functional Relationships(s)
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1 We did find an increase of BDNF protein after a single injection of fingolimod 0.1 or 1.0 mg/kg, but not after multiple injections, indicating that the BDNF response to fingolimod is unsustainable over time. Fingolimod Hydrochloride brain derived neurotrophic factor Mus musculus
2 We did find an increase of BDNF protein after a single injection of fingolimod 0.1 or 1.0 mg/kg, but not after multiple injections, indicating that the BDNF response to fingolimod is unsustainable over time. Fingolimod Hydrochloride brain derived neurotrophic factor Mus musculus