Title : The Protective Effect of Ligustilide in Osteoarthritis: An in Vitro and in Vivo Study.

Pub. Date : 2018

PMID : 30121673






1 Functional Relationships(s)
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1 RESULTS: LIG lowered the phosphorylation levels of p65, IkappaBalpha, and IKKalpha/beta and suppressed the IL-1beta-induced expression of MMP-3, ADAMTS-5, iNOS, and COX-2 and the inflammatory factors PGE2, TNF-alpha, and IL-6. Dinoprostone interleukin 1 beta Mus musculus