Title : Influence of Steroidal enzyme inducers on the toxicity of pyrogallol, pargyline and nialamide.

Pub. Date : 1977 Mar

PMID : 300677






1 Functional Relationships(s)
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1 In rats, the toxic manifestations of overdosage with with parcyline (a monoamine oxidase inhibitor) or pyrogallol (a catechol-o-methyltransferase inhibitor) were diminished by treatment with the more potent steroidal (pregnenolone-16alpha-carbonitrile, spironolactone, etc.) Pregnenolone Carbonitrile catechol-O-methyltransferase Rattus norvegicus