Title : Ketoconazole blocks cortisol secretion in man by inhibition of adrenal 11 beta-hydroxylase.

Pub. Date : 1985 Jul 1

PMID : 2993735






2 Functional Relationships(s)
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1 Ketoconazole induced a rise of 11-deoxycortisol and 11-deoxycorticosterone, but not of cortisol and inconsistently of corticosterone which were increased by ACTH. Ketoconazole proopiomelanocortin Homo sapiens
2 Plasma ACTH levels were stimulated 2-50 fold by ketoconazole. Ketoconazole proopiomelanocortin Homo sapiens