Title : (2E,5E)-2,5-Bis(3-hydroxy-4-methoxybenzylidene) cyclopentanone Exerts Anti-Melanogenesis and Anti-Wrinkle Activities in B16F10 Melanoma and Hs27 Fibroblast Cells.

Pub. Date : 2018 Jun 11

PMID : 29891820






1 Functional Relationships(s)
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1 BHCP was found to potently inhibit tyrosinase, with 50% inhibition concentration (IC50) values of 1.10 microM and 8.18 microM for monophenolase (l-tyrosine) and diphenolase (l-DOPA), and the enzyme kinetics study revealed that BHCP is a competitive-type tyrosinase inhibitor. Tyrosine tyrosinase Homo sapiens