Title : Pannexin-1 channels contribute to seizure generation in human epileptic brain tissue and in a mouse model of epilepsy.

Pub. Date : 2018 May 30

PMID : 29848662






1 Functional Relationships(s)
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1 Pharmacological inhibition of pannexin-1 channels with probenecid or mefloquine-two medications currently used for treating gout and malaria, respectively-blocked ictal discharges in human cortical brain tissue slices. Mefloquine pannexin 1 Homo sapiens