Title : Deciphering the molecular determinants of cholinergic anthelmintic sensitivity in nematodes: When novel functional validation approaches highlight major differences between the model Caenorhabditis elegans and parasitic species.

Pub. Date : 2018 May

PMID : 29719008






1 Functional Relationships(s)
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1 In the model nematode Caenorhabditis elegans, genetic screens led to the identification of five genes encoding levamisole-sensitive-AChR (L-AChR) subunits: unc-38, unc-63, unc-29, lev-1 and lev-8. Levamisole Acetylcholine receptor subunit alpha-type unc-63 Caenorhabditis elegans