Title : Beta-endorphin-induced inhibition and stimulation of insulin secretion in normal humans is glucose dependent.

Pub. Date : 1988 Sep

PMID : 2970411






2 Functional Relationships(s)
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1 Acute insulin and C-peptide responses to intravenous pulses of different glucose amounts (0.33 g/kg and 5 g) and arginine (3 g) were significantly reduced by beta-endorphin infusion (P less than .01). Arginine proopiomelanocortin Homo sapiens
2 beta-Endorphin also inhibited glucose suppression of glucagon levels and augmented the glucagon response to arginine. Arginine proopiomelanocortin Homo sapiens