Title : Analysis of the Indacaterol-Regulated Transcriptome in Human Airway Epithelial Cells Implicates Gene Expression Changes in the Adverse and Therapeutic Effects of β2-Adrenoceptor Agonists.

Pub. Date : 2018 Jul

PMID : 29653961






1 Functional Relationships(s)
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1 Operational model-fitting established that the long-acting beta2-adrenoceptor agonists (LABA) indacaterol, salmeterol, formoterol, and picumeterol were full agonists on BEAS-2B cells transfected with a cAMP-response element reporter but differed in efficacy (indacaterol >= formoterol > salmeterol >= picumeterol). Cyclic AMP adrenoceptor beta 2 Homo sapiens