Title : The beta secretase BACE1 regulates the expression of insulin receptor in the liver.

Pub. Date : 2018 Apr 3

PMID : 29610518






1 Functional Relationships(s)
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1 Here we show that the amount of biologically active IR is regulated by the cleavage of its ectodomain, by the beta-site amyloid precursor protein cleaving enzyme 1 (BACE1), in a glucose concentration-dependent manner. Glucose insulin receptor Homo sapiens