Title : Differential regulation of alcohol taking and seeking by antagonism at α4β2 and α3β4 nAChRs.

Pub. Date : 2018 Jun

PMID : 29572652






2 Functional Relationships(s)
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1 CONCLUSIONS: These findings suggest differential roles for alpha4beta2 and alpha3beta4 nAChR on alcohol taking and seeking with selective blockade of alpha4beta2 nAChR being more implicated in modulating alcohol taking while selective blockade of alpha3beta4 nAChR is involved in nicotine-induced alcohol seeking. Nicotine cholinergic receptor nicotinic beta 1 subunit Rattus norvegicus
2 CONCLUSIONS: These findings suggest differential roles for alpha4beta2 and alpha3beta4 nAChR on alcohol taking and seeking with selective blockade of alpha4beta2 nAChR being more implicated in modulating alcohol taking while selective blockade of alpha3beta4 nAChR is involved in nicotine-induced alcohol seeking. Nicotine cholinergic receptor nicotinic beta 1 subunit Rattus norvegicus