Pub. Date : 2018 Mar 22
PMID : 29565268
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Remarkably, when A549 cells were subjected to hinokitiol (1-5 microM), there was an increase in the activities of antioxidant enzymes catalase (CAT) and superoxide dismutase (SOD) from the reduction in cells. | beta-thujaplicin | superoxide dismutase 1 | Homo sapiens |
2 | Remarkably, when A549 cells were subjected to hinokitiol (1-5 microM), there was an increase in the activities of antioxidant enzymes catalase (CAT) and superoxide dismutase (SOD) from the reduction in cells. | beta-thujaplicin | superoxide dismutase 1 | Homo sapiens |
3 | These observations indicate that hinokitiol inhibited the migration of lung cancer A549 cells through several mechanisms, including the activation of caspases-9 and -3, induction of p53/Bax and antioxidant CAT and SOD, and reduction of MMP-2 and -9 activities. | beta-thujaplicin | superoxide dismutase 1 | Homo sapiens |