Title : Discovery of 18β-glycyrrhetinic acid conjugated aminobenzothiazole derivatives as Hsp90-Cdc37 interaction disruptors that inhibit cell migration and reverse drug resistance.

Pub. Date : 2018 May 1

PMID : 29486954






2 Functional Relationships(s)
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1 Discovery of 18beta-glycyrrhetinic acid conjugated aminobenzothiazole derivatives as Hsp90-Cdc37 interaction disruptors that inhibit cell migration and reverse drug resistance. 18alpha-glycyrrhetinic acid heat shock protein 90 alpha family class A member 1 Homo sapiens
2 A series of 18beta-glycyrrhetinic acid (GA) conjugated aminobenzothiazole derivatives were designed, synthesized and evaluated for disruption activity of Hsp90-Cdc37 as well as the effects of in vitro cell migration. 18alpha-glycyrrhetinic acid heat shock protein 90 alpha family class A member 1 Homo sapiens