Title : The effects of tramadol administration on hippocampal cell apoptosis, learning and memory in adult rats and neuroprotective effects of crocin.

Pub. Date : 2018 Jun

PMID : 29470767






1 Functional Relationships(s)
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1 In tramadol-treated animals, the dark neurons (DNs) and apoptotic cells in CA1, CA3 and DG increased (P < 0.05), while concurrent intake of crocin decreased the number of DNs and apoptotic cells in these areas (P < 0.05). Tramadol carbonic anhydrase 1 Rattus norvegicus