Title : Involvement of TLR3-Dependent PGES Expression in Immunosuppression by Human Bone Marrow Mesenchymal Stem Cells.

Pub. Date : 2018 Apr

PMID : 29273868






3 Functional Relationships(s)
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1 On the other hand, the toll like receptor 3 (TLR3) stimulant poly(I:C) increased expression of both COX-2 and PGES, resulting in a significant increase in PGE2 levels. Dinoprostone prostaglandin E synthase Homo sapiens
2 In summary, the present study reveals that upregulation of PGES via TLR3 is critical for BM-MSCs-mediated immunosuppression by PGE2 secretion via the COX-2/PGE2 pathway. Dinoprostone prostaglandin E synthase Homo sapiens
3 In summary, the present study reveals that upregulation of PGES via TLR3 is critical for BM-MSCs-mediated immunosuppression by PGE2 secretion via the COX-2/PGE2 pathway. Dinoprostone prostaglandin E synthase Homo sapiens