Pub. Date : 2017 Dec
PMID : 29272017
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Selective cyclooxygenase-2 inhibitor NS-398 attenuates myocardial fibrosis in mice after myocardial infarction via Snail signaling pathway. | N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide | snail family zinc finger 1 | Mus musculus |
2 | OBJECTIVE: The role of NS-398 in Snail pathway of myocardial cells in mice after myocardial infarction and its effect on myocardial fibrosis were investigated in this study. | N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide | snail family zinc finger 1 | Mus musculus |
3 | The administration of NS-398 for 3 weeks inhibited the Snail activity expression and significantly improved the fibrosis degree after infarction. | N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide | snail family zinc finger 1 | Mus musculus |
4 | CONCLUSIONS: NS-398 improves the myocardial fibrosis in mice after myocardial infarction through inhibiting the Snail signaling pathway. | N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide | snail family zinc finger 1 | Mus musculus |