Pub. Date : 2018 Feb
PMID : 29268182
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Metyrapone blocks cortisol synthesis, removing negative feedback, and increases the release of hypothalamic CRF and pituitary adrenocorticotropic hormone (ACTH). | Metyrapone | proopiomelanocortin | Homo sapiens |
| 2 | Metyrapone resulted in a greater increase in ACTH and greater decreases in cortisol and delta spectral power sleep in PTSD subjects compared to controls, and a greater increase in ACTH in women compared to men. | Metyrapone | proopiomelanocortin | Homo sapiens |
| 3 | Metyrapone resulted in a greater increase in ACTH and greater decreases in cortisol and delta spectral power sleep in PTSD subjects compared to controls, and a greater increase in ACTH in women compared to men. | Metyrapone | proopiomelanocortin | Homo sapiens |