Title : A Trimeric HIV-1 Envelope gp120 Immunogen Induces Potent and Broad Anti-V1V2 Loop Antibodies against HIV-1 in Rabbits and Rhesus Macaques.

Pub. Date : 2018 Mar 1

PMID : 29237847






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 These results demonstrate that cycP-gp120 serves as a robust HIV Env immunogen that induces broad anti-V1V2 antibodies and promotes neutralization breadth against HIV-1.IMPORTANCE Recent focus in HIV-1 vaccine development has been the design of trimeric HIV-1 Env immunogens that closely resemble native HIV-1 Env, with a major goal being the induction of bNAbs. bnabs inter-alpha-trypsin inhibitor heavy chain 4 Homo sapiens