Title : Endocannabinoid hydrolases in avian HD11 macrophages identified by chemoproteomics: inactivation by small-molecule inhibitors and pathogen-induced downregulation of their activity.

Pub. Date : 2018 Jul

PMID : 29196970






1 Functional Relationships(s)
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1 We identified alpha/beta-hydrolase domain 6 (ABHD6) and fatty acid amide hydrolase (FAAH) as the principal SHs responsible for 2-arachidonoylglycerol (2AG) hydrolysis, thereby regulating the concentration of this lipid in HD11 cells. glyceryl 2-arachidonate fatty acid amide hydrolase Gallus gallus