Title : Effects of peroxisome proliferator activated receptors (PPAR)-γ and -α agonists on cochlear protection from oxidative stress.

Pub. Date : 2017

PMID : 29182629






1 Functional Relationships(s)
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1 Pioglitazone (PPARgamma-specific), tesaglitazar (PPARgamma/alpha-specific), and fenofibric acid (PPARalpha-specific) all provided >90% protection from gentamicin toxicity by regulation of overlapping subsets of genes controlling ROS detoxification. fenofibric acid peroxisome proliferator activated receptor alpha Mus musculus