Title : The mitochondrial metabolic reprogramming agent trimetazidine as an 'exercise mimetic' in cachectic C26-bearing mice.

Pub. Date : 2017 Dec

PMID : 29130633






1 Functional Relationships(s)
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1 RESULTS: Our data showed that TMZ induces some effects typically achieved through exercise, among which is grip strength increase, an enhanced fast-to slow myofibre phenotype shift, reduced glycaemia, PGC1alpha up-regulation, oxidative metabolism, and mitochondrial biogenesis. Trimetazidine peroxisome proliferative activated receptor, gamma, coactivator 1 alpha Mus musculus