Title : Hereditary spastic paraplegia type 5: natural history, biomarkers and a randomized controlled trial.

Pub. Date : 2017 Dec 1

PMID : 29126212






1 Functional Relationships(s)
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1 Biochemically, marked accumulation of CYP7B1 substrates including 27-hydroxycholesterol was confirmed in serum (n = 19) and cerebrospinal fluid (n = 17) of SPG5 patients. 27-hydroxycholesterol cytochrome P450 family 7 subfamily B member 1 Homo sapiens