Title : [Synergistic Killing Effects of Arsenic Trioxide Combined with Itraconazole on KG1a Cells].

Pub. Date : 2017 Aug

PMID : 28823259






1 Functional Relationships(s)
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1 CONCLUSION: Arsenic trioxide combined with itraconazole can inhibit the KG1a cell proliferation and induce apoptosis, which may be related with the inhibition of Hh signaling pathway and upregulation of both Caspase-3 and BAX protein expression, and provided experimental data of arsenic trioxide combined with itraconazole for the treatment of refractory AML. Arsenic Trioxide caspase 3 Homo sapiens