Title : [Synergistic Killing Effects of Arsenic Trioxide Combined with Itraconazole on KG1a Cells].

Pub. Date : 2017 Aug

PMID : 28823259

1 Functional Relationships(s)
Compound Name
Protein Name
1 CONCLUSION: Arsenic trioxide combined with itraconazole can inhibit the KG1a cell proliferation and induce apoptosis, which may be related with the inhibition of Hh signaling pathway and upregulation of both Caspase-3 and BAX protein expression, and provided experimental data of arsenic trioxide combined with itraconazole for the treatment of refractory AML. Arsenic Trioxide caspase 3 Homo sapiens