Title : Anti-inflammatory mechanism of galangin in lipopolysaccharide-stimulated microglia: Critical role of PPAR-γ signaling pathway.

Pub. Date : 2017 Nov 15

PMID : 28757373






1 Functional Relationships(s)
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1 Pretreatment with a PPAR-gamma antagonist or siRNA significantly blocked galangin-mediated upregulation of IL-10 and attenuated the inhibition of tumor necrosis factor (TNF)-alpha, nitric oxide (NO), and IL-6 in LPS-stimulated microglia. Nitric Oxide peroxisome proliferator activated receptor gamma Mus musculus