Title : The alpha-7 nicotinic acetylcholine receptor is involved in a direct inhibitory effect of nicotine on GnRH release: In vitro studies.

Pub. Date : 2018 Jan 15

PMID : 28754351






2 Functional Relationships(s)
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1 However, nicotine was found to modify GnRH pulsatility in perifusion experiments and inhibits, the release of GnRH induced by prostaglandin E1 or by K+-induced cell depolarization; these effects were reversed by D-tubocurarine and alpha-bungarotoxin. Tubocurarine gonadotropin releasing hormone 1 Mus musculus
2 However, nicotine was found to modify GnRH pulsatility in perifusion experiments and inhibits, the release of GnRH induced by prostaglandin E1 or by K+-induced cell depolarization; these effects were reversed by D-tubocurarine and alpha-bungarotoxin. Tubocurarine gonadotropin releasing hormone 1 Mus musculus