Title : BNIP3 induction by hypoxia stimulates FASN-dependent free fatty acid production enhancing therapeutic potential of umbilical cord blood-derived human mesenchymal stem cells.

Pub. Date : 2017 Oct

PMID : 28704726






2 Functional Relationships(s)
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1 Silencing of BNIP3 suppressed free fatty acid (FFA) synthesis regulated by SREBP1/FASN pathway, which is involved in UCB-hMSC apoptosis via caspases cleavage and migration via cofilin-1-mediated F-actin reorganization in hypoxia. Fatty Acids, Nonesterified sterol regulatory element binding transcription factor 1 Homo sapiens
2 Silencing of BNIP3 suppressed free fatty acid (FFA) synthesis regulated by SREBP1/FASN pathway, which is involved in UCB-hMSC apoptosis via caspases cleavage and migration via cofilin-1-mediated F-actin reorganization in hypoxia. Fatty Acids, Nonesterified sterol regulatory element binding transcription factor 1 Homo sapiens