Title : Therapeutic effect of icariin combined with stem cells on postmenopausal osteoporosis in rats.

Pub. Date : 2018 Mar

PMID : 28681147






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1 Icariin combined with stem cells significantly reduced body weight gain caused by ovariectomy, significantly decreased alkaline phosphatase, tartrate-resistant acid phosphatase, and bone gamma-carboxyglutamate protein content in serum, significantly increased osteoprotegerin content, significantly elevated bone mineral density of the lumbar spine, left femur, and right femur, and enhanced bone biomechanical properties of the femur, including maximum bending load, bending rigidity, and fracture energy, in osteoporotic rats. icariin bone gamma-carboxyglutamate protein Rattus norvegicus