Title : Ketoconazole treatment in Cushing's disease. Effect on the circadian profile of plasma ACTH and cortisol.

Pub. Date : 1988 Nov

PMID : 2852693






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1 We have evaluated by chronobiological procedures the circadian profiles of plasma ACTH and cortisol in three patients with Cushing"s disease before and after a six-month course of therapy with ketoconazole (600 mg daily). Ketoconazole proopiomelanocortin Homo sapiens