Pub. Date : 2017 May 11
PMID : 28492556
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | PLSCR1/IP3R1/Ca2+ axis contributes to differentiation of primary AML cells induced by wogonoside. | wogonoside | phospholipid scramblase 1 | Homo sapiens |
| 2 | We have demonstrated that wogonoside possesses differentiation and anti-leukemic effects in AML cell lines by promoting PLSCR1 trafficking into nucleus. | wogonoside | phospholipid scramblase 1 | Homo sapiens |
| 3 | Here we report that wogonoside promotes the expression of PLSCR1 and enhances its nuclear translocation and binding to the 1, 4, 5-trisphosphate receptor 1 (IP3R1) promoter in AML patient-derived primary cells. | wogonoside | phospholipid scramblase 1 | Homo sapiens |