Title : Rutin Protects against Pirarubicin-Induced Cardiotoxicity through TGF-β1-p38 MAPK Signaling Pathway.

Pub. Date : 2017

PMID : 28367221






1 Functional Relationships(s)
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1 Administration of RUT and SB203580, both individually as well as in combination, suppressed the elevation of intracellular ROS, inhibited cell apoptosis, and reversed the THP-induced upregulation of TGF-beta1, p-p38 MAPK, cleaved Caspase-9, Caspase-7, and Caspase-3. pirarubicin caspase 7 Rattus norvegicus