Title : P450 inhibitor ketoconazole increased the intratumor drug levels and antitumor activity of fenretinide in human neuroblastoma xenograft models.

Pub. Date : 2017 Jul 15

PMID : 28340497






1 Functional Relationships(s)
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1 We previously reported that concurrent ketoconazole, an oral anti-fungal agent and P450 enzyme inhibitor, increased plasma levels of the cytotoxic retinoid, fenretinide (4-HPR) in mice. Fenretinide haptoglobin-related protein Homo sapiens