Title : Nicotine facilitates VSMC dysfunction through a miR-200b/RhoGDIA/cytoskeleton module.

Pub. Date : 2017 Mar 2

PMID : 28252009

1 Functional Relationships(s)
Compound Name
Protein Name
1 Here, we found that nicotine can activate the Rho GTPase pathway and induce the synthesis of the cytoskeletal proteins in VSMCs through the activation of intracellular downstream signaling pathways, including targets such as MYPT1, PAK1 and PI3K/AKT. Nicotine AKT serine/threonine kinase 1 Homo sapiens