Title : [Effect of Arsenic Trioxide on K562 Cell Proliferation and Its Mechanism].

Pub. Date : 2017 Feb

PMID : 28245381






1 Functional Relationships(s)
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1 CONCLUSION: ATO in certain concentration range can inhibit K562 cell proliferation, and induce the cell apotosis, the mechanismin influencing the Wnt/beta-catenin pathway may be the downregulation of CD44 expression, arresting K562 cells in G0/G1 phase, and affecting the gene transcription, thus inhibiting K562 cell proliferation. ato CD44 molecule (Indian blood group) Homo sapiens