Title : Angiotensin-II-induced Muscle Wasting is Mediated by 25-Hydroxycholesterol via GSK3β Signaling Pathway.

Pub. Date : 2017 Feb

PMID : 28161398






1 Functional Relationships(s)
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1 Intraperitoneal injection of 25-hydroxycholesterol (25-OHC), the product of Ch25h, resulted in muscle loss in C57BL/6 mice, accompanied by increased expression of atrogin-1, MuRF1 and suppression of IGF-1/Akt signaling pathway. 25-hydroxycholesterol cholesterol 25-hydroxylase Mus musculus