Title : Human Ig knockin mice to study the development and regulation of HIV-1 broadly neutralizing antibodies.

Pub. Date : 2017 Jan

PMID : 28133799






1 Functional Relationships(s)
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1 Since 2010, immunoglobulin knockin (KI) technology, involving inserting functional rearranged human variable exons into the mouse IgH and IgL loci has been used to express bnAbs in mice. bnabs immunoglobulin heavy chain complex Mus musculus