Title : Ceramide 1-Phosphate Increases P-Glycoprotein Transport Activity at the Blood-Brain Barrier via Prostaglandin E2 Signaling.

Pub. Date : 2017 Apr

PMID : 28119480






1 Functional Relationships(s)
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1 Inhibition of the key signaling components in the cyclooxygenase-2 (COX-2)/prostaglandin E2 signaling cascade (phospholipase A2, COX-2, multidrug resistance protein 4, and G-protein-coupled prostaglandin E2 receptors 1 and 2), abolished P-glycoprotein induction by C1P. Dinoprostone prostaglandin-endoperoxide synthase 2 Rattus norvegicus